C. Senthil Kumari


The present study was aimed to evaluate the effect of mirabilis jalapa Linn on anti implantation activity of female albino wistar rats.The animals were treated with ethanolic extract of mirabilis jalapa , with doses of 200 mg and 400 mg/kg body weight from day 1 to day 7 of pregnancy. The rats were sacrified on day 10 of pregnancy.Presence of foetus, implantation sites and number of corporal lutea were recorded.There was a 100% reduction in pregnancy was observed in 400 mg/kg of Mirabilis jalapa and it showed  maximum percent inhibition or reduction when compared with control.All the rats were delivered in control groups,where as 30% of rats delivered in 200 mg/kg of Mirabilis jalapa Linn when compared to control.Biochemical changes were observed in Blood Glucose, Cholestrol, triglycerides. In 400 mg/kg of Ethanolic Extract of Mirabilis jalapa Linn showed depletion in Blood Glucose, Cholestrol, Triglycerides when compared with control. In 200 mg/kg it showed less depletion of blood glucose, Cholestrol and Triglycerides when compared with control


Anti implantation ,Mirabilis jalapa ,acute toxicity studies.


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Zhou JY, Zhou SW, Zeng SY, Zhous Jy, Jiang MJ, He Y. Hypoglycemic and Hypolipidemic Effects of Ethanolic Extract of Mriabilis jalapa Linn Root on Normal and Diabetic Mice. Evidence Based Complementary Alternative Medicine. 2012:257-374

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Aoki Ethanopharmacological Review of Four O Clock Flower Plant Mirabilis jalapa Linn.1960;19:297-317.

Gogoi J,Nakhuru KS et al., Isolation and Characterization of Bioactive components from Mirabilis jalapa Linn radix. J.Tradit Complement Med.2015 Jan 27;6(1):41-7.

Hanumantappa Bherigi Nayaka, Ramesh Londonkar. Evaluation of Portulaca Oleracea for Anti-Fertility Effect in Female Albino Rats 2014. 6(5). 0975-1491

Sunil Kumar Shah, Deenanath, Jhade. Anti-fertility activity of Ethanolic and Aqueous Extracts of Aloe Vera Mill on Female Winsar Rats Rising Approaches of herbal contraception. Journal of Pharmaceutical Sciences and Research. 2016; 8(9):952 – 957

Parimal P. Katolkar, Bhumesh. Anti-Implantation activity of the Methanolic Extract of Corida Dichotoma Lam. Bark in Rats. International Journal of Bio-Medical and Advance Research, 2012;3(3)

Ramesh Londonkar and Hanumantappa, Evaluation of Anti implantation and Abortificient properties of Portulaca Oleracea L in albino rats, 2011. 2(4):0975-6299




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