ANTI-IMPLANTATION ACTIVITY OF THE ETHANOLIC EXTRACT OF MIRABILIS JALAPA LINN IN FEMALE ALBINO WISTAR RATS

C. Senthil Kumari

Abstract


The present study was aimed to evaluate the effect of mirabilis jalapa Linn on anti implantation activity of female albino wistar rats.The animals were treated with ethanolic extract of mirabilis jalapa , with doses of 200 mg and 400 mg/kg body weight from day 1 to day 7 of pregnancy. The rats were sacrified on day 10 of pregnancy.Presence of foetus, implantation sites and number of corporal lutea were recorded.There was a 100% reduction in pregnancy was observed in 400 mg/kg of Mirabilis jalapa and it showed  maximum percent inhibition or reduction when compared with control.All the rats were delivered in control groups,where as 30% of rats delivered in 200 mg/kg of Mirabilis jalapa Linn when compared to control.Biochemical changes were observed in Blood Glucose, Cholestrol, triglycerides. In 400 mg/kg of Ethanolic Extract of Mirabilis jalapa Linn showed depletion in Blood Glucose, Cholestrol, Triglycerides when compared with control. In 200 mg/kg it showed less depletion of blood glucose, Cholestrol and Triglycerides when compared with control


Keywords


Anti implantation ,Mirabilis jalapa ,acute toxicity studies.

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URN: https://pmindexing.com/index.php/IJCPA/issue/view/urn:pmi:jr:0011ijcpa.v5i2.14552

DOI: https://pmindexing.com/91.1211/ijcpa.v5i2.1455

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