Biological Screening of Newly Synthesized Schiff base, (Z)-2-(1-(2,5-dimethoxyphenylimino)ethyl)phenol and its complexes.

ramachandran sathya

Abstract


Abstract:

Some newly mixed metal complexes were synthesized using (Z)-2-(1-(2,5-dimethoxyphenylimino) ethyl) phenol ligand (L) and metal ions (M) = Cu (II), Mn (II), V (II) and Au (III).  The ligand and metal complexes were characterized quantitatively and qualitatively by using, Elemental analysis, Infrared spectra, Electronic spectra. Elemental analysis of the metal complexes was suggested that the stoichiometry ratio is 1:2 (metal-ligand). Fluorescent studies also have been reported. The electronic spectrum provides clear idea about the metal complexes. The Schiff base complexes have been screened for their in-vitro biological activities against and bacteria and fungi. Anti-bacterial activity against three bacteria via; [Staphylococcus aureus, Bacillus sp., (Gram-positive) Pseudomonas aeruginosa (Gram-negative)] and Antifungal activities (Aspergillus Niger and Aspergillus flavus). Anti-oxidant properties of metal complexes also have been studied. The metal complexes show more potential activities compared with Schiff base ligands.

Keywords:    

               Schiff base, Transition metal complexes, spectroscopy, Fluorescent studies,           Biological   Screening, Anti-oxidant studies.

 


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URN: https://pmindexing.com/index.php/IJCPA/issue/view/urn:pmi:jr:0011ijcpa.v5i2.14495

DOI: https://pmindexing.com/91.1211/ijcpa.v5i2.1449

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